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Tsutomu Imaizumi Selected Research

1- O- hexadecyl- 2- (5- oxovaleroyl)- sn- glycerophosphocholine

1/2002Core aldehydes of alkyl glycerophosphocholines in atheroma induce platelet aggregation and inhibit endothelium-dependent arterial relaxation.

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Tsutomu Imaizumi Research Topics

Disease

24Hypertension (High Blood Pressure)
01/2018 - 01/2002
24Inflammation (Inflammations)
02/2014 - 01/2005
24Atherosclerosis
02/2014 - 10/2000
18Fibrosis (Cirrhosis)
01/2014 - 07/2002
17Hypertrophy
11/2012 - 07/2002
15Insulin Resistance
10/2014 - 02/2003
15Diabetic Retinopathy (Retinopathy, Diabetic)
10/2009 - 04/2004
12Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 10/2005
11Ischemia
01/2015 - 03/2002
9Neoplasms (Cancer)
01/2012 - 07/2003
9Diabetic Angiopathies (Diabetic Angiopathy)
11/2008 - 01/2005
8Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2014 - 05/2005
8Coronary Artery Disease (Coronary Atherosclerosis)
11/2013 - 06/2005
7Atherosclerotic Plaque (Atheroma)
01/2015 - 01/2002
7Type 2 Diabetes Mellitus (MODY)
11/2013 - 03/2007
6Heart Failure
10/2014 - 02/2003
6Hyperglycemia
10/2011 - 01/2005
5Atrial Fibrillation
03/2016 - 10/2002
5Myocardial Infarction
10/2014 - 01/2008
5Cardiomegaly (Heart Hypertrophy)
01/2014 - 12/2006
5Glucose Intolerance
11/2013 - 05/2007
5Hypercholesterolemia
12/2008 - 02/2002
4Abdominal Aortic Aneurysm
01/2018 - 06/2011
4Chronic Renal Insufficiency
01/2015 - 08/2006
4Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2014 - 12/2003
4Thrombosis (Thrombus)
03/2008 - 01/2002
4Vascular System Injuries
06/2007 - 05/2003
3Aortic Dissection
01/2020 - 04/2004
3Infections
01/2019 - 09/2003
3Stroke (Strokes)
07/2015 - 09/2004
3Vascular Remodeling
01/2015 - 09/2003
3Hypoxia (Hypoxemia)
01/2015 - 01/2002
3Essential Hypertension
01/2014 - 11/2005
3Diabetes Mellitus
11/2013 - 05/2007
3Carotid Artery Diseases
10/2011 - 09/2004
3Obesity
04/2011 - 02/2003
3Thromboangiitis Obliterans (Buerger's Disease)
01/2011 - 08/2007
3Pulmonary Hypertension
05/2010 - 12/2004
3Melanoma (Melanoma, Malignant)
01/2008 - 04/2004
3Hepatocellular Carcinoma (Hepatoma)
10/2007 - 05/2006
3Uveitis
09/2007 - 02/2007
3Neointima
06/2007 - 12/2003
3Eye Diseases (Eye Disease)
01/2007 - 04/2004
2Infarction (Infarctions)
10/2014 - 02/2012
2Hypotension (Low Blood Pressure)
01/2014 - 03/2005
2Tachycardia (Tachyarrhythmias)
01/2014 - 03/2012

Drug/Important Bio-Agent (IBA)

25Advanced Glycation End ProductsIBA
12/2012 - 12/2004
25pigment epithelium-derived factorIBA
11/2012 - 04/2004
14Angiotensin IIIBA
01/2018 - 03/2002
12HDL CholesterolIBA
10/2013 - 02/2003
11Proteins (Proteins, Gene)FDA Link
10/2014 - 01/2003
11Biomarkers (Surrogate Marker)IBA
11/2013 - 03/2007
10Glucose (Dextrose)FDA LinkGeneric
02/2014 - 02/2003
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2008 - 01/2002
9Transforming Growth Factor beta (TGF-beta)IBA
10/2009 - 10/2000
8Triglycerides (Triacylglycerol)IBA
01/2014 - 02/2003
8Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
03/2011 - 08/2004
7Receptor for Advanced Glycation End ProductsIBA
01/2011 - 06/2005
6Uric Acid (Urate)IBA
01/2014 - 02/2003
6C-Reactive ProteinIBA
05/2013 - 05/2006
6Insulin (Novolin)FDA Link
02/2012 - 02/2003
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2009 - 05/2004
5Hydrochlorothiazide (Esidrix)FDA LinkGeneric
01/2018 - 07/2012
5Losartan (Cozaar)FDA LinkGeneric
01/2018 - 07/2012
5Angiotensin Receptor AntagonistsIBA
01/2018 - 10/2008
5Messenger RNA (mRNA)IBA
01/2015 - 07/2002
5CytokinesIBA
01/2015 - 01/2005
5LipidsIBA
11/2013 - 01/2002
5Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2013 - 04/2005
5Transforming Growth Factors (Transforming Growth Factor)IBA
03/2011 - 03/2003
5NADPH Oxidases (NAD(P)H oxidase)IBA
10/2009 - 06/2005
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2008 - 01/2005
4Antihypertensive Agents (Antihypertensives)IBA
07/2015 - 02/2009
4Pioglitazone (Actos)FDA Link
11/2013 - 10/2011
4N,N-dimethylarginine (asymmetric dimethylarginine)IBA
10/2013 - 08/2006
4Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
07/2013 - 05/2005
4LDL CholesterolIBA
01/2013 - 06/2007
4CreatinineIBA
04/2012 - 02/2003
4CholesterolIBA
01/2012 - 02/2002
4oxidized low density lipoproteinIBA
01/2011 - 07/2002
4Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2008 - 06/2005
3glimepiride (Amarel)FDA LinkGeneric
11/2013 - 10/2011
3AlbuminsIBA
01/2013 - 04/2004
3LDL Lipoproteins (beta Lipoproteins)IBA
01/2013 - 07/2002
3Leucine (L-Leucine)FDA Link
11/2012 - 08/2003
3Brain Natriuretic Peptide (Natrecor)FDA Link
11/2012 - 12/2006
3Endothelin-1 (Endothelin 1)IBA
01/2012 - 08/2003
3Simvastatin (Zocor)FDA LinkGeneric
03/2011 - 11/2006
3candesartanIBA
10/2009 - 02/2004
3Superoxides (Superoxide)IBA
03/2008 - 06/2005
3Dipyridamole (Persantine)FDA LinkGeneric
01/2008 - 06/2005
3Interferon-gamma (Interferon, gamma)IBA
08/2007 - 03/2007
3Retinaldehyde (Retinal)IBA
01/2007 - 01/2005
3Caveolin 3IBA
03/2005 - 08/2003
3Neutralizing AntibodiesIBA
04/2004 - 07/2002
2olmesartanIBA
10/2014 - 01/2008

Therapy/Procedure

19Therapeutics
01/2018 - 07/2002
6Denervation
01/2014 - 10/2009
3Intravenous Injections
04/2013 - 03/2008
3Transplantation
05/2010 - 03/2002